Humira vs Enbrel
Both TNF blockers for arthritis. Humira treats more conditions; Enbrel may have slightly lower infection risk. Biosimilars available for both.
Side-by-Side Comparison
| Humira | Enbrel | |
|---|---|---|
| Generic Name | Adalimumab | Etanercept |
| Manufacturer | AbbVie | Amgen |
| FDA Uses | Rheumatoid arthritis, Psoriatic arthritis, Crohn's disease, Ulcerative colitis, Plaque psoriasis, Hidradenitis suppurativa | Rheumatoid arthritis, Psoriatic arthritis, Ankylosing spondylitis, Plaque psoriasis |
| Dosing | 40mg every other week injection | 50mg weekly injection |
| Monthly Cost | $5,800 | $5,500 |
| With Insurance | $5–$500 | $5–$500 |
| Common Side Effects | Injection site reactions, Upper respiratory infections, Headache | Injection site reactions, Upper respiratory infections, Headache |
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Frequently Asked Questions
Which is better, Humira or Enbrel?
Both TNF blockers for arthritis. Humira treats more conditions; Enbrel may have slightly lower infection risk. Biosimilars available for both. The best choice depends on your specific condition, insurance coverage, and how your body responds. Talk to your doctor about which is right for you.
Is Humira cheaper than Enbrel?
Humira costs $5,800/month while Enbrel costs $5,500/month without insurance. With insurance, copays may be similar depending on your plan's formulary.
Can I switch from Humira to Enbrel?
Switching between these medications should only be done under your doctor's supervision. They may need to adjust dosing and monitor for side effects during the transition.
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