Abilify vs Seroquel
Both atypical antipsychotics. Seroquel is more sedating; Abilify is more activating. Both are used as depression add-ons.
Abilify
Aripiprazole · Otsuka/Bristol-Myers Squibb
Atypical antipsychotic for multiple mental health conditions
Seroquel
Quetiapine · AstraZeneca
Atypical antipsychotic for schizophrenia and bipolar disorder
Side-by-Side Comparison
| Abilify | Seroquel | |
|---|---|---|
| Generic Name | Aripiprazole | Quetiapine |
| Manufacturer | Otsuka/Bristol-Myers Squibb | AstraZeneca |
| FDA Uses | Schizophrenia, Bipolar disorder, Major depressive disorder (adjunct), Autism irritability | Schizophrenia, Bipolar disorder, Major depressive disorder (adjunct) |
| Dosing | 2-30mg once daily | 25-800mg daily |
| Monthly Cost | $950 | $580 |
| With Insurance | $10–$60 | $5–$40 |
| Common Side Effects | Weight gain, Restlessness, Insomnia, Drowsiness | Drowsiness, Weight gain, Dry mouth, Dizziness |
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Frequently Asked Questions
Which is better, Abilify or Seroquel?
Both atypical antipsychotics. Seroquel is more sedating; Abilify is more activating. Both are used as depression add-ons. The best choice depends on your specific condition, insurance coverage, and how your body responds. Talk to your doctor about which is right for you.
Is Abilify cheaper than Seroquel?
Abilify costs $950/month while Seroquel costs $580/month without insurance. With insurance, copays may be similar depending on your plan's formulary.
Can I switch from Abilify to Seroquel?
Switching between these medications should only be done under your doctor's supervision. They may need to adjust dosing and monitor for side effects during the transition.
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