Ozempic vs Trulicity
Both weekly GLP-1 injections for diabetes. Ozempic shows greater A1C reduction and weight loss in head-to-head trials.
Side-by-Side Comparison
| Ozempic | Trulicity | |
|---|---|---|
| Generic Name | Semaglutide | Dulaglutide |
| Manufacturer | Novo Nordisk | Eli Lilly |
| FDA Uses | Type 2 diabetes, Cardiovascular risk reduction | Type 2 diabetes, Cardiovascular risk reduction |
| Dosing | 0.25mg, 0.5mg, or 1mg weekly injection | 0.75mg or 1.5mg weekly injection |
| Monthly Cost | $935 | $970 |
| With Insurance | $25–$150 | $25–$150 |
| Common Side Effects | Nausea, Diarrhea, Vomiting, Constipation, Abdominal pain | Nausea, Diarrhea, Vomiting, Abdominal pain, Decreased appetite |
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Frequently Asked Questions
Which is better, Ozempic or Trulicity?
Both weekly GLP-1 injections for diabetes. Ozempic shows greater A1C reduction and weight loss in head-to-head trials. The best choice depends on your specific condition, insurance coverage, and how your body responds. Talk to your doctor about which is right for you.
Is Ozempic cheaper than Trulicity?
Ozempic costs $935/month while Trulicity costs $970/month without insurance. With insurance, copays may be similar depending on your plan's formulary.
Can I switch from Ozempic to Trulicity?
Switching between these medications should only be done under your doctor's supervision. They may need to adjust dosing and monitor for side effects during the transition.
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