Letrozole vs Clomid
Studies show letrozole may produce higher live birth rates than Clomid for unexplained infertility, with fewer multiple pregnancies.
Side-by-Side Comparison
| Letrozole (Femara) | Clomid | |
|---|---|---|
| Generic Name | Letrozole | Clomiphene Citrate |
| Manufacturer | Novartis | Sanofi |
| FDA Uses | Breast cancer | Ovulatory dysfunction (infertility) |
| Dosing | 2.5-7.5mg daily for 5 days (fertility); 2.5mg daily (cancer) | 50-150mg daily for 5 days |
| Monthly Cost | $30 | $40 |
| With Insurance | $3–$15 | $5–$25 |
| Common Side Effects | Hot flashes, Headache, Fatigue, Joint pain | Hot flashes, Bloating, Mood swings, Visual disturbances |
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Frequently Asked Questions
Which is better, Letrozole (Femara) or Clomid?
Studies show letrozole may produce higher live birth rates than Clomid for unexplained infertility, with fewer multiple pregnancies. The best choice depends on your specific condition, insurance coverage, and how your body responds. Talk to your doctor about which is right for you.
Is Letrozole (Femara) cheaper than Clomid?
Letrozole (Femara) costs $30/month while Clomid costs $40/month without insurance. With insurance, copays may be similar depending on your plan's formulary.
Can I switch from Letrozole (Femara) to Clomid?
Switching between these medications should only be done under your doctor's supervision. They may need to adjust dosing and monitor for side effects during the transition.
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